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recombinant human igf-1 (rhigf-1  (PeproTech)


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    Structured Review

    PeproTech recombinant human igf-1 (rhigf-1
    Recombinant Human Igf 1 (Rhigf 1, supplied by PeproTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+igf-1+(rhigf-1/igf+1+growth+factor/pmc11743118-31-0-7
    Average 90 stars, based on 1 article reviews
    recombinant human igf-1 (rhigf-1 - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Recombinant:

    Article Title: IGF-1 facilitates thrombopoiesis primarily through Akt activation.
    Article Snippet: Primary MKs were treated with recombinant human IGF-1 (rhIGF-1) (Peprotech, Rocky Hill, NJ) at 37 °C, and were then lysed by the addition of 2 × immunoprecipitation buffer (10 mM Tris, 1% Nonidet P-40, 5 mM EDTA, 1 mM Na3VO4, 0.5 mM phenylmethanesulfonyl fluoride, 150 mM NaCl, pH 7.4) containing a protease inhibitor cocktail (Roche Applied Science, Penzberg, Germany), and rotated at 4 °C for 1h.

    Article Title: IGF-1:tetanus toxin fragment C fusion protein improves delivery of IGF-1 to spinal cord but fails to prolong survival of ALS mice.
    Article Snippet: Ru-Ju Chian, Jianhong Li, Ilknur Ay, Samuel A. Celia, Brenda B. Kashi, Eric Tamrazian, Jonathan C. Matthews, Roderick T. Bronson, Anthony Rossomando, R. Blake Pepinsky, Paul S. Fishman, Robert H. Brown Jr. , Jonathan W. Francis⁎ Cecil B.. Day Laboratory for Neuromuscular Research, Department of Neurology, Massachusetts General Hospital, Building 114, 16th Street, Room 3003, Charlestown, MA 02129, USA Rodent Histopathology Core, Dana Farber/Harvard Cancer Center, Boston, MA 02115, USA BiogenIdec, Inc., 14 Cambridge Center, Cambridge, MA 02142, USA Research Service, Baltimore Veterans Affairs Medical Center, Baltimore, MD 21201, USA Department of Neurology, University of Maryland School of Medicine, Baltimore, MD 21201, USA

    Article Title: IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution.
    Article Snippet: Recombinant human IGF-1 (rhIGF-1) was obtained from PeproTech.

    Article Title: A Role for Insulin-like Growth Factor 1 in the Generation of Epileptic Spasms in a murine model.
    Article Snippet: Objective: Infantile spasms are associated with a wide variety of clinical conditions, including perinatal brain injuries.. We have created a model in which prolonged infusion of tetrodotoxin (TTX) into the neocortex, beginning in infancy, produces a localized lesion and reproduces the behavioral spasms, electroencephalogram (EEG) abnormalities, and drug responsiveness seen clinically.. Here, we undertook experiments to explore the possibility that the growth factor IGF-1 plays a role in generating epileptic spasms.

    Immunoprecipitation:

    Article Title: IGF-1 facilitates thrombopoiesis primarily through Akt activation.
    Article Snippet: Primary MKs were treated with recombinant human IGF-1 (rhIGF-1) (Peprotech, Rocky Hill, NJ) at 37 °C, and were then lysed by the addition of 2 × immunoprecipitation buffer (10 mM Tris, 1% Nonidet P-40, 5 mM EDTA, 1 mM Na3VO4, 0.5 mM phenylmethanesulfonyl fluoride, 150 mM NaCl, pH 7.4) containing a protease inhibitor cocktail (Roche Applied Science, Penzberg, Germany), and rotated at 4 °C for 1h.

    Article Title: IGF-1:tetanus toxin fragment C fusion protein improves delivery of IGF-1 to spinal cord but fails to prolong survival of ALS mice.
    Article Snippet: Ru-Ju Chian, Jianhong Li, Ilknur Ay, Samuel A. Celia, Brenda B. Kashi, Eric Tamrazian, Jonathan C. Matthews, Roderick T. Bronson, Anthony Rossomando, R. Blake Pepinsky, Paul S. Fishman, Robert H. Brown Jr. , Jonathan W. Francis⁎ Cecil B.. Day Laboratory for Neuromuscular Research, Department of Neurology, Massachusetts General Hospital, Building 114, 16th Street, Room 3003, Charlestown, MA 02129, USA Rodent Histopathology Core, Dana Farber/Harvard Cancer Center, Boston, MA 02115, USA BiogenIdec, Inc., 14 Cambridge Center, Cambridge, MA 02142, USA Research Service, Baltimore Veterans Affairs Medical Center, Baltimore, MD 21201, USA Department of Neurology, University of Maryland School of Medicine, Baltimore, MD 21201, USA

    Article Title: IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution.
    Article Snippet: Recombinant human IGF-1 (rhIGF-1) was obtained from PeproTech.

    Article Title: A Role for Insulin-like Growth Factor 1 in the Generation of Epileptic Spasms in a murine model.
    Article Snippet: Objective: Infantile spasms are associated with a wide variety of clinical conditions, including perinatal brain injuries.. We have created a model in which prolonged infusion of tetrodotoxin (TTX) into the neocortex, beginning in infancy, produces a localized lesion and reproduces the behavioral spasms, electroencephalogram (EEG) abnormalities, and drug responsiveness seen clinically.. Here, we undertook experiments to explore the possibility that the growth factor IGF-1 plays a role in generating epileptic spasms.

    Protease Inhibitor:

    Article Title: IGF-1 facilitates thrombopoiesis primarily through Akt activation.
    Article Snippet: Primary MKs were treated with recombinant human IGF-1 (rhIGF-1) (Peprotech, Rocky Hill, NJ) at 37 °C, and were then lysed by the addition of 2 × immunoprecipitation buffer (10 mM Tris, 1% Nonidet P-40, 5 mM EDTA, 1 mM Na3VO4, 0.5 mM phenylmethanesulfonyl fluoride, 150 mM NaCl, pH 7.4) containing a protease inhibitor cocktail (Roche Applied Science, Penzberg, Germany), and rotated at 4 °C for 1h.

    Article Title: IGF-1:tetanus toxin fragment C fusion protein improves delivery of IGF-1 to spinal cord but fails to prolong survival of ALS mice.
    Article Snippet: Ru-Ju Chian, Jianhong Li, Ilknur Ay, Samuel A. Celia, Brenda B. Kashi, Eric Tamrazian, Jonathan C. Matthews, Roderick T. Bronson, Anthony Rossomando, R. Blake Pepinsky, Paul S. Fishman, Robert H. Brown Jr. , Jonathan W. Francis⁎ Cecil B.. Day Laboratory for Neuromuscular Research, Department of Neurology, Massachusetts General Hospital, Building 114, 16th Street, Room 3003, Charlestown, MA 02129, USA Rodent Histopathology Core, Dana Farber/Harvard Cancer Center, Boston, MA 02115, USA BiogenIdec, Inc., 14 Cambridge Center, Cambridge, MA 02142, USA Research Service, Baltimore Veterans Affairs Medical Center, Baltimore, MD 21201, USA Department of Neurology, University of Maryland School of Medicine, Baltimore, MD 21201, USA

    Article Title: IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution.
    Article Snippet: Recombinant human IGF-1 (rhIGF-1) was obtained from PeproTech.

    Article Title: A Role for Insulin-like Growth Factor 1 in the Generation of Epileptic Spasms in a murine model.
    Article Snippet: Objective: Infantile spasms are associated with a wide variety of clinical conditions, including perinatal brain injuries.. We have created a model in which prolonged infusion of tetrodotoxin (TTX) into the neocortex, beginning in infancy, produces a localized lesion and reproduces the behavioral spasms, electroencephalogram (EEG) abnormalities, and drug responsiveness seen clinically.. Here, we undertook experiments to explore the possibility that the growth factor IGF-1 plays a role in generating epileptic spasms.

    Activity Assay:

    Article Title: IGF-1 facilitates thrombopoiesis primarily through Akt activation.
    Article Snippet: Primary MKs were treated with recombinant human IGF-1 (rhIGF-1) (Peprotech, Rocky Hill, NJ) at 37 °C, and were then lysed by the addition of 2 × immunoprecipitation buffer (10 mM Tris, 1% Nonidet P-40, 5 mM EDTA, 1 mM Na3VO4, 0.5 mM phenylmethanesulfonyl fluoride, 150 mM NaCl, pH 7.4) containing a protease inhibitor cocktail (Roche Applied Science, Penzberg, Germany), and rotated at 4 °C for 1h.

    Article Title: IGF-1:tetanus toxin fragment C fusion protein improves delivery of IGF-1 to spinal cord but fails to prolong survival of ALS mice.
    Article Snippet: Ru-Ju Chian, Jianhong Li, Ilknur Ay, Samuel A. Celia, Brenda B. Kashi, Eric Tamrazian, Jonathan C. Matthews, Roderick T. Bronson, Anthony Rossomando, R. Blake Pepinsky, Paul S. Fishman, Robert H. Brown Jr. , Jonathan W. Francis⁎ Cecil B.. Day Laboratory for Neuromuscular Research, Department of Neurology, Massachusetts General Hospital, Building 114, 16th Street, Room 3003, Charlestown, MA 02129, USA Rodent Histopathology Core, Dana Farber/Harvard Cancer Center, Boston, MA 02115, USA BiogenIdec, Inc., 14 Cambridge Center, Cambridge, MA 02142, USA Research Service, Baltimore Veterans Affairs Medical Center, Baltimore, MD 21201, USA Department of Neurology, University of Maryland School of Medicine, Baltimore, MD 21201, USA

    Article Title: IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution.
    Article Snippet: Recombinant human IGF-1 (rhIGF-1) was obtained from PeproTech.

    Article Title: A Role for Insulin-like Growth Factor 1 in the Generation of Epileptic Spasms in a murine model.
    Article Snippet: Objective: Infantile spasms are associated with a wide variety of clinical conditions, including perinatal brain injuries.. We have created a model in which prolonged infusion of tetrodotoxin (TTX) into the neocortex, beginning in infancy, produces a localized lesion and reproduces the behavioral spasms, electroencephalogram (EEG) abnormalities, and drug responsiveness seen clinically.. Here, we undertook experiments to explore the possibility that the growth factor IGF-1 plays a role in generating epileptic spasms.

    Purification:

    Article Title: IGF-1 facilitates thrombopoiesis primarily through Akt activation.
    Article Snippet: Primary MKs were treated with recombinant human IGF-1 (rhIGF-1) (Peprotech, Rocky Hill, NJ) at 37 °C, and were then lysed by the addition of 2 × immunoprecipitation buffer (10 mM Tris, 1% Nonidet P-40, 5 mM EDTA, 1 mM Na3VO4, 0.5 mM phenylmethanesulfonyl fluoride, 150 mM NaCl, pH 7.4) containing a protease inhibitor cocktail (Roche Applied Science, Penzberg, Germany), and rotated at 4 °C for 1h.

    Article Title: IGF-1:tetanus toxin fragment C fusion protein improves delivery of IGF-1 to spinal cord but fails to prolong survival of ALS mice.
    Article Snippet: Ru-Ju Chian, Jianhong Li, Ilknur Ay, Samuel A. Celia, Brenda B. Kashi, Eric Tamrazian, Jonathan C. Matthews, Roderick T. Bronson, Anthony Rossomando, R. Blake Pepinsky, Paul S. Fishman, Robert H. Brown Jr. , Jonathan W. Francis⁎ Cecil B.. Day Laboratory for Neuromuscular Research, Department of Neurology, Massachusetts General Hospital, Building 114, 16th Street, Room 3003, Charlestown, MA 02129, USA Rodent Histopathology Core, Dana Farber/Harvard Cancer Center, Boston, MA 02115, USA BiogenIdec, Inc., 14 Cambridge Center, Cambridge, MA 02142, USA Research Service, Baltimore Veterans Affairs Medical Center, Baltimore, MD 21201, USA Department of Neurology, University of Maryland School of Medicine, Baltimore, MD 21201, USA

    Article Title: IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution.
    Article Snippet: Recombinant human IGF-1 (rhIGF-1) was obtained from PeproTech.

    Article Title: A Role for Insulin-like Growth Factor 1 in the Generation of Epileptic Spasms in a murine model.
    Article Snippet: Objective: Infantile spasms are associated with a wide variety of clinical conditions, including perinatal brain injuries.. We have created a model in which prolonged infusion of tetrodotoxin (TTX) into the neocortex, beginning in infancy, produces a localized lesion and reproduces the behavioral spasms, electroencephalogram (EEG) abnormalities, and drug responsiveness seen clinically.. Here, we undertook experiments to explore the possibility that the growth factor IGF-1 plays a role in generating epileptic spasms.



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